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作者:Scott G. Turner
来源:[B].Brain and Spinal Tumors - Primary and Secondary2020
摘要:Standard therapy for malignant gliomas includes maximal resection followed by radiotherapy and temozolomide. The increase in neovascularization in high-grade gliomas serves the increased metabolic demands of these fast-growing tumors and the main pathway mediating this process in...
作者:Cuili Ma, Pengfei Ji, Nina Xie and Yujing Li
来源:[B].Chromatin and Epigenetics2020
摘要:Vast emerging evidences are linking the base modifications and gene expression involved in essential metabolic pathways. Among the base modification markers extensively studied, 5-methylcytosine (5mC) and its oxidative derivatives (5-hydroxymethylcytosine (5-hmC), 5-formylcytosin...
作者:Wesley Carpenter
来源:[B].Toward Super-Creativity - Improving Creativity in Humans, Machines, and Human - Machine Collaborations2020
摘要:Insight, often referred to as an “aha moment,” has been defined as a sudden, conscious change in a person’s representation of a stimulus, situation, event, or problem. Recent advances in neuroimaging technology and neurophysiological techniques have allowed researchers ...
作者:In Young Moon and Jin-Wook Kim
来源:[B].Chromatin and Epigenetics2020
摘要:Hepatitis B virus (HBV) is the most important cause of chronic viral hepatitis worldwide. The genome of HBV is 3.2 kb partially double-stranded DNA, which is translocated to the nuclei of infected hepatocytes and converted to complete double-stranded DNA, aka covalently closed ci...
作者:Joyce Pauline Joseph
来源:[B].Multiple Sclerosis2020
摘要:Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central nervous system. Although there are no pathognomonic features to confirm the diagnosis of this immune-mediated disease, a constellation of clinical, radiological, and immune studies can ensure ...
作者:Koen Olthuis, Kasirajan Mahalingam, Pierre-Baptiste Tartas and Chris Zevenbergen
来源:[B].Habitats of the World - Biodiversity and Threats2020
摘要:A previous study by the authors found that most slum physical upgrading projects traditionally focus on basic services, elaborated with citywide data, without addressing locational and environmental aspects. However, such data tends to hide the highly heterogeneous nature of...
作者:Saleh Rasras and Arash Kiani
来源:[B].Brain and Spinal Tumors - Primary and Secondary2020
摘要:Intradural extramedullary (IDEM) spinal tumors are common pathologies, and despite their name, they can extend beyond dural confinements. IDEMs can have both sporadic and syndromic patterns, and various genetic abnormalities are believed to be responsible for these mainly benign ...
作者:Lambros Messinis, Grigorios Nasios and Panagiotis Papathanasopouos
来源:[B].Multiple Sclerosis2020
摘要:Although cognitive difficulties are not frequently reported by patients among the initial symptoms of Multiple Sclerosis (MS), there is sufficient evidence that cognitive impairment is present from the early stage of the disease. Today it is commonly accepted that roughly one-hal...
作者:Paul Enríquez
来源:[B].Chromatin and Epigenetics2020
摘要:The regulation of chromatin structure and gene expression depends substantially on a dynamic and intricate layer of biological and chemical information that constitutes the epigenome. This epigenetic layer of information holds fundamental clues to the molecular mechanisms, n...
作者:Seyyedeh Zahra Safi
来源:[B].Multiple Sclerosis2020
摘要:The aim of this chapter is to assess the effectiveness of non-pharmacologic therapies like progressive muscle relaxation therapy (PMRT) as an adjunctive therapy for reducing level of depression for multiple sclerosis (MS) patients. One of the most common mood disorders is ma...

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