European Cells and Materials (eCM)
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作者:W Boot , C Jiao , P G Nikkels ...
来源:[J].Eur Cell Mater(IF 4.558), 2020, Vol.39, pp.108-120European Cells and Materials (eCM)
摘要:Local prophylaxis with antibiotic-loaded bone cement is a successful method to prevent post-operative infections in patients receiving orthopaedic implants. No comparable method is available for uncemented implants. Therefore, a hydrogel consisting of hyaluronic and polylactic ac...
作者:C C Lee , C Jiao , E Gersz ...
来源:[J].Eur Cell Mater(IF 4.558), 2020, Vol.39, pp.96-107European Cells and Materials (eCM)
摘要:Staphylococcus aureus (S. aureus) osteomyelitis remains a major clinical problem. Anti-glucosaminidase (Gmd) antibodies (1C11) are efficacious in prophylactic and therapeutic murine models. Feasibility, safety and pharmacokinetics of 1C11 passive immunisation in sheep and en...
作者:S M Shiels , J C Wenke
来源:[J].Eur Cell Mater(IF 4.558), 2020, Vol.39, pp.77-95European Cells and Materials (eCM)
摘要:Orthopaedic implant use increases infection risk. Implant infection risk can be explained by the “race for the surface” concept, where there is competition between host-cell integration and bacterial colonisation. Although generally accepted, the temporal dynamics have not b...
作者:E Delve , V Co , S C Regmi ...
来源:[J].Eur Cell Mater(IF 4.558), 2020, Vol.39, pp.48-64European Cells and Materials (eCM)
摘要:The roles of cell division control protein 42 homologue (CDC42) and actin polymerisation in regulating the phenotype of superficial-zone chondrocytes (SZCs) have been demonstrated in vitro; however, the signalling pathway(s) downstream have yet to be fully elucidated. The study h...
作者:M Fusellier , J Clouet , O Gauthier ...
来源:[J].Eur Cell Mater(IF 4.558), 2020, Vol.39, pp.18-47European Cells and Materials (eCM)
摘要:Appropriate cell sources, bioactive factors and biomaterials for generation of functional and integrated annulus fibrosus (AF) tissue analogues are still an unmet need. In the present study, the AF cell markers, collagen type I, cluster of differentiation 146 (CD146), mohawk...
作者:J Du , R G Long , T Nakai ...
来源:[J].Eur Cell Mater(IF 4.558), 2020, Vol.39, pp.1-17European Cells and Materials (eCM)
摘要:Appropriate cell sources, bioactive factors and biomaterials for generation of functional and integrated annulus fibrosus (AF) tissue analogues are still an unmet need. In the present study, the AF cell markers, collagen type I, cluster of differentiation 146 (CD146), mohawk...
作者:R Black , A J Grodzinsky
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.246-263European Cells and Materials (eCM)
摘要:While glucocorticoids have been used for over 50 years to treat rheumatoid and osteoarthritis pain, the prescription of glucocorticoids remains controversial because of potentially harmful side effects at the molecular, cellular and tissue levels. One member of the glucocort...
作者:O F Gardner , S C Juneja , H Whetstone ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.215-227European Cells and Materials (eCM)
摘要:In an effort to develop an effective source of clinically relevant cells and tissues for cartilage repair a directed differentiation method was used to generate articular chondrocytes and cartilage tissues from human embryonic stem cells (hESCs). It has previously been demonstrat...
作者:M W Laschke , M S Seifert , C Scheuer ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.188-200European Cells and Materials (eCM)
摘要:High glucose concentrations have been shown to activate endothelial cells and promote angiogenesis. In the present study, it was investigated whether high glucose concentrations could improve the vascularisation capacity of adipose-tissue-derived microvascular fragments (ad-...
作者:I Irastorza , J Luzuriaga , R Martinez-Conde ...
来源:[J].Eur Cell Mater(IF 4.558), 2019, Vol.38, pp.201-214European Cells and Materials (eCM)
摘要:Dental implants are the usual therapy of choice in the dental clinic to replace a loss of natural teeth. Over recent decades there has been an important progress in the design and manufacturing of titanium implant surfaces with the goal of improving their osteointegration. I...

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