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作者:Xuchen Xu , Jianing Zhang , Xin Yang ...
来源:[J].Journal of Immunology Research, 2020, Vol.2020
摘要:Asthma, the most common chronic respiratory disease in children, affects numerous people worldwide. Accumulating evidence suggests that exposure to high levels of particulate matter (PM), either acutely or chronically, is associated with the exacerbation and incidence of pediatri...
作者:Yong Wang , Xuemei Cui , Lijia Yuan ...
来源:[J].Journal of Immunology Research, 2020, Vol.2020
摘要:Pseudorabies is an important infectious disease of swine, and immunization using attenuated pseudorabies virus (aPrV) vaccine is a routine practice to control this disease in swine herds. This study was to evaluate a saline solution containing ginseng stem-leaf saponins (GSL...
作者:Kateryna Pierzynowska , Jarosław Woliński , Björn Weström ...
来源:[J].Journal of Immunology Research, 2020, Vol.2020
摘要:The current study is aimed at highlighting the impact of enterally or parenterally applied immunoglobulins (Igs) on polyunsaturated fatty acid (PUFA) absorption in newborn pigs. Piglets were chosen as the appropriate model since they are born agammaglobulinemic and any effects of...
作者:Xiaojie Li , Wenying Zhou , Yanlan Liang ...
来源:[J].Journal of Immunology Research, 2020, Vol.2020
摘要:Signal regulatory protein α (SIRP α ), a transmembrane protein that is predominantly expressed in dendritic cells (DCs) or macrophages, interacts with CD47 that is overexpressed in almost all types of tumor cells. The interaction between SIRP α and CD47 leads to a negative s...
作者:Xuchu Gu , Zhiyu Ma , Jing Fang ...
来源:[J].Journal of Immunology Research, 2020, Vol.2020
摘要:Obese mice exhibited more lymphocytes in the bronchoalveolar lavage fluid and milder lung injury after Escherichia coli ( E. coli ) infection. However, it remained unclear whether the spleen contributed to the effect of obese mice with infection. The study was purposed to re...
作者:Chaopin Yang , Yue Li , Yaozhang Yang ...
来源:[J].Journal of Immunology Research, 2020, Vol.2020
摘要:NK cells are lymphocytes with antitumor properties and can directly lyse tumor cells in a non-MHC-restricted manner. However, the tumor microenvironment affects the immune function of NK cells, which leads to immune evasion. This may be related to the pathogenesis of some disease...
作者:Thayse Pinheiro da Costa , Marcia Cury El-Cheikh , Katia Carneiro ...
来源:[J].Journal of Immunology Research, 2020, Vol.2020
摘要:Histone Deacetylase- (HDAC-) dependent epigenetic mechanisms have been widely explored in the last decade in different types of malignancies in preclinical studies. This effort led to the discovery and development of a range of new HDAC inhibitors (iHDAC) with different chem...
作者:Thushari Gunawardana , Khawaja Ashfaque Ahmed , Kalhari Goonewardene ...
来源:[J].Journal of Immunology Research, 2020, Vol.2020
摘要:Immunoprotective function of oligodeoxynucleotides containing CpG motifs (CpG-ODN) has been demonstrated in neonatal chickens against common bacterial pathogens such as E.coli and Salmonella sp. Our recent study reported that CpG-ODN administration enriches immune compartmen...
作者:Yuanyuan Li , Yueqi Song , Leqing Zhu ...
来源:[J].Journal of Immunology Research, 2020, Vol.2020
摘要:Type I interferon kappa (IFN κ ) is selectively expressed in human keratinocytes. Herpes simplex virus-1 (HSV-1) is a human pathogen that infects keratinocytes and causes lytic skin lesions. Whether IFN κ plays a role in keratinocyte host defense against HSV-1 has not been i...
作者:Piotr Witczak , Ewa Brzezińska-Błaszczyk , Justyna Agier ...
来源:[J].Journal of Immunology Research, 2020, Vol.2020
摘要:Mast cells (MCs) are found mainly at the anatomical sites exposed to the external environment; thus, they are localized close to blood vessels, lymphatic vessels, and a multitude of immune cells. Moreover, those cells can recognize invading pathogens through a range of surfa...

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